Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378660 | 0.87 | HTT (0.58) | HTTKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8580742 | 0.86 | ALDH1A1 (0.54) | HTTKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8231868 | 0.82 | ALDH1A1 (0.54) | PKMHTTALDH1A1MAPTRAB9A | |
| SCHEMBL11422683 | 0.81 | PKM (0.66) | PKMHTTKDM4EMAPTRAB9A | |
| SCHEMBL9175285 | 0.80 | CYP1A2 (0.61) | PKMHTTMAPTRAB9ANPC1 | |
| SCHEMBL10850026 | 0.80 | PKM (0.50) | PKMHTTALDH1A1MAPTRAB9A | |
| SCHEMBL11432520 | 0.79 | PKM (0.62) | PKMHTTRAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL10549586 | 0.78 | PKM (0.49) | PKMHTTALDH1A1MAPTRAB9A | |
| SCHEMBL8536932 | 0.77 | PKM (0.58) | PKMHTTMAPTRAB9ANPC1 | |
| SCHEMBL30986309 | 0.77 | MAPT (0.63) | PKMHTTKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792780-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0657449-B1 | Azole compounds, their production and use as antifungal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5545652-A | Triazole and imidazole compounds and their use as antifungal therapeutic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0657449-A1 | Azole compounds, their production and use as antifungal agents | Takeda Chemical Industries, Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |