SCHEMBL48603

SCHEMBL48603

CCSc1cc(C)c(N)c(SCC)c1N

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AOC3 Q16853 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522764 0.94 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL8764612 0.90
SCHEMBL8540338 0.89 AOC3 (0.38) ALDH1A1AOC3MAPT
SCHEMBL6911477 0.89 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL8764562 0.89 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL1797285 0.88
SCHEMBL9184128 0.87 ALDH1A1 (0.40) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL9179742 0.82 ALDH1A1 (0.36) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL6912224 0.81 KMT2A (0.34) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL48321 0.79 AOC3 (0.36) ALDH1A1AOC3MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3298061-B1 A CURING AGENT FOR THERMOSETTING EPOXY RESINS, AND A PROCESS FOR THE PREPARATION OF INSULATION SYSTEMS FOR ELECTRICAL ENGINEERING HUNTSMAN ADVANCED MAT LICENSING (SWITZERLAND) GMBH (CH) 2020-09-09 EP claimed
EP-3083744-B1 POLYURETHANE/POLYUREAS COVESTRO LLC (US) 2020-04-22 EP claimed
US-20180142058-A1 A Curing Agent For Thermosetting Epoxy Resins, and a Process for the Preparation of Insulation Systems for Electrical Engineering HUNTSMAN INTERNATIONAL LLC (US) 2018-05-24 US claimed
EP-3298061-A1 A CURING AGENT FOR THERMOSETTING EPOXY RESINS, AND A PROCESS FOR THE PREPARATION OF INSULATION SYSTEMS FOR ELECTRICAL ENGINEERING Huntsmann Advanced Materials Licensing (Switzerland) GmbH (CH) 2018-03-28 EP claimed
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US claimed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US claimed
WO-2016184749-A1 A CURING AGENT FOR THERMOSETTING EPOXY RESINS, AND A PROCESS FOR THE PREPARATION OF INSULATION SYSTEMS FOR ELECTRICAL ENGINEERING HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2016-11-24 WO claimed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP claimed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO claimed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US claimed
US-6939907-B2 Golf balls comprising highly-neutralized acid polymers ACUSHNET COMPANY (US) 2005-09-06 US claimed
US-6894098-B2 Golf balls comprising highly-neutralized acid polymers ACUSHNET COMPANY (US) 2005-05-17 US claimed
US-20050009638-A1 Golf ball layers formed of polyurethane-based and polyurea-based compositions incorporating block copolymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-20040209708-A1 Water resistant polyurea elastomers for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-10-21 US claimed
US-20030158352-A1 Golf balls comprising highly-neutralized acid polymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-08-21 US claimed
US-20030144087-A1 Golf balls comprising highly-neutralized acid polymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-07-31 US claimed
EP-0635034-B1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEM CO INC (US) 1997-07-30 EP claimed
EP-0635034-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM. UNIROYAL CHEM CO INC (US) 1995-01-25 EP claimed
WO-1993021247-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-28 WO claimed
US-4595742-A Formed by reacting polyisocyanate, an organic active hydrogen group containing compound, and a chain extender comprising an aromatic diamine ETHYL CORPORATION (US) 1986-06-17 US claimed