Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481443 | 0.87 | SRC (0.48) | TPMTPTGS2SRCAKR1C3AKR1C2 | |
| SCHEMBL23066460 | 0.82 | SRC (0.48) | TPMTPTGS2SRCAKR1C3AKR1C2 | |
| SCHEMBL8538429 | 0.81 | ACP3 (0.47) | PTGS2SRCAKR1C3AKR1C2HTT | |
| SCHEMBL6953631 | 0.81 | TPMT (0.43) | TPMTPTGS2SRCAKR1C3AKR1C2 | |
| SCHEMBL3584535 | 0.73 | TPMT (0.48) | TPMTPTGS2AKR1C3AKR1C2RXRA | |
| SCHEMBL5846200 | 0.71 | PTGS2 (0.54) | TPMTPTGS2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL6397570 | 0.71 | LMNA (0.50) | TPMTPTGS2AKR1C3AKR1C2RXRA | |
| SCHEMBL1573370 | 0.71 | LMNA (0.50) | TPMTPTGS2AKR1C3AKR1C2RXRA | |
| SCHEMBL1573368 | 0.71 | LMNA (0.50) | TPMTPTGS2AKR1C3AKR1C2RXRA | |
| SCHEMBL8960142 | 0.71 | PTGS2 (0.54) | TPMTPTGS2AKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |