Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538112 | 0.90 | DRD3 (0.44) | ADRA1AHRH1DRD2DRD4HTR2A | |
| SCHEMBL8541398 | 0.90 | P2RX7 (0.51) | ALOX5DRD2DRD3P2RX7 | |
| SCHEMBL8537394 | 0.87 | DRD3 (0.51) | ADRA1AHRH1DRD2DRD4HTR2A | |
| SCHEMBL8541391 | 0.78 | ACHE (0.49) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL8541258 | 0.77 | P2RX7 (0.55) | ALOX5HTR7P2RX7 | |
| SCHEMBL8539201 | 0.75 | HRH1 (0.54) | ADRA1AHRH1DRD2DRD4HTR2A | |
| SCHEMBL22252849 | 0.72 | ACHE (0.78) | ACHEADRA1AADRA1BHRH1DRD2 | |
| SCHEMBL8536410 | 0.72 | DRD3 (0.46) | ADRA1AALOX5HRH1DRD2DRD4 | |
| SCHEMBL8541786 | 0.71 | HRH1 (0.56) | ADRA1AADRA1BHRH1DRD2HTR2A | |
| SCHEMBL22252847 | 0.70 | ACHE (0.66) | ACHEADRA1AADRA1BHRH1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508334-B1 | Novel aminophenol derivatives and pharmaceutical compositions thereof | GREEN CROSS CORP (JP) | 1998-01-07 | — | — | EP | claimed |
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | claimed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | claimed |
| EP-0508334-B1 | Novel aminophenol derivatives and pharmaceutical compositions thereof | GREEN CROSS CORP (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |