SCHEMBL8540431

SCHEMBL8540431

COCc1ccccc1C(=O)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.43
HIF1A Q16665 5/20 0.43
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 2/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.39
CTSD P07339 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1190027 0.85 TSHR (0.49) LMNAALDH1A1KMT2ATSHRHPGD
SCHEMBL4234379 0.84 POLB (0.47) PRMT5HIF1ALMNAALDH1A1HDAC3
SCHEMBL8307369 0.83 HIF1A (0.55) HIF1ALMNAALDH1A1TSHRHPGD
SCHEMBL1189675 0.83 PRMT5 (0.41) PRMT5LMNAALDH1A1HDAC3HDAC1
SCHEMBL30463198 0.82 ALDH1A1 (0.46) HIF1ALMNAALDH1A1KMT2ATSHR
SCHEMBL3306441 0.82 ALDH1A1 (0.42) HIF1ALMNAALDH1A1KMT2ATSHR
SCHEMBL7487933 0.82 ALDH1A1 (0.46) HIF1ALMNAALDH1A1KMT2ATSHR
SCHEMBL3150175 0.81 ALDH1A1 (0.62) HIF1ALMNAALDH1A1KMT2ATSHR
SCHEMBL9267454 0.81 HDAC3 (0.42) PRMT5HIF1ALMNAALDH1A1HDAC3
SCHEMBL9021316 0.81 HDAC3 (0.42) PRMT5HIF1ALMNAALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4242199-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS XII BASF SE (DE) 2023-09-13 EP disclosed
EP-0684226-B1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF AG (DE) 1998-05-06 EP disclosed
EP-0684225-B1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF AG (DE) 1997-07-23 EP disclosed
EP-0513580-B1 Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides BASF AG (DE) 1996-10-23 EP disclosed
EP-0499823-B1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF AG (DE) 1996-06-05 EP disclosed
EP-0684226-A1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1995-11-29 EP disclosed
EP-0684225-A1 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1995-11-29 EP disclosed
US-5416068-A Alpha-phenylacrylic acid derivatives, their preparation and their use for controlling pests and harmful fungi BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US disclosed
US-5298527-A Insecticides BASF AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
US-5254717-A Imino-substituted phenyl derivatives, the preparation thereof and fungicides containing these BASF AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
EP-0513580-A2 Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides BASF Aktiengesellschaft (DE) 1992-11-19 EP disclosed
EP-0499823-A2 Imino-substituted phenyl derivatives, their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1992-08-26 EP disclosed