Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051400 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL5597833 | 0.83 | TSHR (0.50) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL28139529 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL8540431 | 0.82 | PRMT5 (0.43) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL30463198 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL7487933 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL2802347 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRCFTRHSD17B10 | |
| SCHEMBL5597965 | 0.81 | TSHR (0.40) | ALDH1A1TSHRKMT2AHTT | |
| SCHEMBL5997915 | 0.81 | HPGD (0.41) | ALDH1A1LMNAHPGDTSHRCTSD | |
| SCHEMBL13361111 | 0.80 | HIF1A (0.45) | ALDH1A1LMNAHPGDTSHRCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113778-A1 | PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2010-05-06 | — | — | US | disclosed |
| US-20100113778-A1 | PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2010-05-06 | — | — | US | disclosed |
| US-20100113778-A1 | PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2010-05-06 | — | — | US | disclosed |
| EP-2134673-A1 | IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009037230-A2 | IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2009-03-26 | — | — | WO | disclosed |
| WO-2008125592-A1 | IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008125592-A1 | IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2008-10-23 | — | — | WO | disclosed |
| US-6126743-A | REACTING THREE DIFFERENT METAL OXIDES OR COMPOUNDS OF SPECIFIC DIAMETERS, FIRING OR HEATING THE MIXTURE AT A TEMPERATURE 400-1200 DEGREE C AT WHICH CRYSTAL PHASE CAN BE FORMED | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-03 | — | — | US | disclosed |
| US-6124493-A | Process for the preparation of o-chloromethyl-phenylglyoxylic acid derivatives | NOVARTIS FINANCE CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| US-6121476-A | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0811612-A1 | Process for preparing dithiocarbonimide derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0777645-A1 | OXIME ETHERS AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1997-06-11 | — | — | EP | disclosed |
| US-5554578-A | Oxime ether derivatives, their preparation and fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| US-5468717-A | Oxime ether derivatives, their preparation and fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| US-5334577-A | 2-(substituted pyridy-oxymethyl)-phenylglyoxylate alkyloxime | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0363818-B1 | Oximether derivatives, process for their preparation and fungicides containing them | BASF AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0374811-B1 | SULFUR-BEARING OXIME ETHERS AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1993-03-03 | — | — | EP | disclosed |
| US-5089528-A | SULFUR-CONTAINING OXIME ETHERS AND FUNGICIDES CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0374811-A1 | Sulfur-bearing oxime ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-06-27 | — | — | EP | disclosed |
| EP-0363818-A1 | Oximether derivatives, process for their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113778-A1 | PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | CYP4F12, GRHPR, CYP4F2 | ALDH1A1 3214/4885LMNA 3502/4885HPGD 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.