SCHEMBL8540443

SCHEMBL8540443

Sn1nnc(-c2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
NPC1 O15118 3/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
MAPK1 P28482 2/20 0.48
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
ATM Q13315 1/20 0.46
TSHR P16473 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8317326 0.77 RAB9A (0.34) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL4414873 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL2210395 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL4411089 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL5289701 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL4405559 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL344042 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL4403726 0.74 RAB9A (0.58) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL20816371 0.74 RAB9A (0.53) RAB9AL3MBTL1NPC1CYP1A2CYP2D6
SCHEMBL2210517 0.72 NPC1 (0.77) RAB9AL3MBTL1NPC1ALDH1A1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190085208-A1 POLISHING COMPOSITION, METHOD FOR PRODUCING SAME, POLISHING METHOD, AND METHOD FOR PRODUCING SUBSTRATE FUJIMI INCORPORATED (JP) 2019-03-21 US disclosed
EP-0797789-B1 NOVEL DIHYDRAZIDES AS DOT-PROMOTING AGENTS IN PHOTOGRAPHIC IMAGE SYSTEMS INT PAPER CO (US) 1998-11-25 EP disclosed
EP-0840614-A1 CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SANOFI WINTHROP, INC. (US) 1998-05-13 EP disclosed
US-5702866-A SHARP IMAGES ILFORD A.G. (CH) 1997-12-30 US disclosed
EP-0797789-A1 NOVEL DIHYDRAZIDES AS DOT-PROMOTING AGENTS IN PHOTOGRAPHIC IMAGE SYSTEMS ILFORD AG (CH) 1997-10-01 EP disclosed
WO-1996041638-A1 CALPAIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SANOFI WINTHROP, INC. (US) 1996-12-27 WO disclosed
WO-1995032452-A1 NOVEL DIHYDRAZIDES AS DOT-PROMOTING AGENTS IN PHOTOGRAPHIC IMAGE SYSTEMS ILFORD AG (CH) 1995-11-30 WO disclosed
EP-0573609-A1 PHOTOSENSITIVE COMPOSITIONS CONTAINING COMB POLYMER BINDERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-15 EP disclosed
WO-1992015628-A1 PHOTOSENSITIVE COMPOSITIONS CONTAINING COMB POLYMER BINDERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-17 WO disclosed