SCHEMBL8317326

SCHEMBL8317326

Sn1nnc(-c2c[c]ccc2)n1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPC1 O15118 2/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA5 P30532 1/20 0.31
CHRNA4 P43681 1/20 0.31
HPGD P15428 1/20 0.31
ATM Q13315 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1823663 0.79 PPARA (0.40) RAB9AL3MBTL1NPC1SMN1; SMN2
SCHEMBL5249745 0.79 NPC1 (0.35) RAB9AL3MBTL1NPC1CHRNB2CHRNA5
SCHEMBL8540443 0.77 RAB9A (0.53) RAB9AL3MBTL1CYP1A2CYP2D6CYP2C19
SCHEMBL5507759 0.77 LMNA (0.53) RAB9AL3MBTL1SMN1; SMN2
SCHEMBL160790 0.67 CYP2A6 (0.45) RAB9ANPC1SMN1; SMN2
SCHEMBL610112 0.67 ALDH1A1 (0.33)
SCHEMBL29190516 0.67 NPC1 (0.39) RAB9AL3MBTL1NPC1HPGDSMN1; SMN2
SCHEMBL28663752 0.66 L3MBTL1 (0.50) RAB9AL3MBTL1NPC1HPGDATM
SCHEMBL9454465 0.64 CYP2A6 (0.33) RAB9ANPC1SMN1; SMN2
SCHEMBL1099384 0.64 ADH5 (0.53) RAB9AL3MBTL1NPC1ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782042-B1 Hydrazine compound and silver halide photographic photosensitive material comprising the same FUJI PHOTO FILM CO LTD (JP) 1999-12-01 EP disclosed
EP-0782041-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-11-17 EP disclosed
US-5981138-A PHOTOSENSITIVE PHOTOGRAPHIC MATERIAL CONTAINS A MESOIONIC RING CONTAINING HYDRAZINE COMPOUND; STABILITY AND EXCELLENT STORABILITY FUJI PHOTO FILM CO., LTD. (JP) 1999-11-09 US disclosed
US-5789139-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1998-08-04 US disclosed
US-5770344-A AROMATIC HYDRAZIDE DERIVATIVE; HIGH CONTRAST; PROCESSING AND STORAGE STABILITY; GRAPHIC ARTS FUJI PHOTO FILM CO., LTD. (JP) 1998-06-23 US disclosed
EP-0782042-A2 Hydrazine compound and silver halide photographic photosensitive material comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1997-07-02 EP disclosed
EP-0782041-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1997-07-02 EP disclosed