Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 5/20 | 0.53 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240727 | 0.83 | CYP26A1 (0.64) | CYP26A1CYP51A1 | |
| SCHEMBL24240734 | 0.76 | CYP26A1 (0.72) | CYP26A1CYP51A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3101929 | 0.74 | ROCK1 (0.67) | CYP26A1CYP51A1 | |
| SCHEMBL8539081 | 0.73 | ADRA2C (0.59) | — | |
| SCHEMBL8536156 | 0.73 | CYP2A6 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8537060 | 0.71 | ALDH1A1 (0.47) | CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8537061 | 0.71 | ALDH1A1 (0.42) | CYP26A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8536035 | 0.71 | CYP19A1 (0.46) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24240721 | 0.70 | CYP51A1 (0.82) | CYP51A1 | |
| SCHEMBL6192902 | 0.69 | ADRA2C (0.54) | CYP51A1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683156-B1 | Acylated aminoalkanimidazoles and -triazoles | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5622982-A | ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS | SANDOZ LTD. (CH) | 1997-04-22 | — | — | US | disclosed |
| EP-0683156-A1 | Acylated aminoalkanimidazoles and -triazoles | SANDOZ LTD. (CH) | 1995-11-22 | — | — | EP | disclosed |