Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.63 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897862 | 0.89 | NPC1 (0.71) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL6234451 | 0.86 | LMNA (0.72) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL7933620 | 0.86 | ALDH1A1 (0.71) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL17830759 | 0.84 | ALDH1A1 (0.69) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL11167021 | 0.84 | NPC1 (0.72) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL28389973 | 0.84 | ALDH1A1 (0.69) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL29500234 | 0.84 | ALDH1A1 (0.69) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL29776932 | 0.82 | CYP3A4 (1.00) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL707208 | 0.82 | CYP3A4 (1.00) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 | |
| SCHEMBL11584604 | 0.82 | ALDH1A1 (1.00) | CYP3A4ALDH1A1MAPK1HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |
| US-5667975-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans | THE UNIVERSITY OF NORTH CAROLINA | 1997-09-16 | — | — | US | disclosed |
| EP-0758453-A1 | METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1997-02-19 | — | — | EP | disclosed |
| US-5594138-A | MEDICAL DIAGNOSIS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996040997-A1 | METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1995030901-A1 | METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-11-16 | — | — | WO | disclosed |