Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790264 | 0.83 | PRNP (0.53) | IKBKBMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL790477 | 0.81 | PRNP (0.52) | IKBKBMEN1KMT2AALDH1A1CA1 | |
| Lithium SCHEMBL790479 | 0.81 | PRNP (0.52) | IKBKBMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL5195648 | 0.80 | IKBKB (0.74) | IKBKBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL30972572 | 0.80 | IKBKB (0.74) | IKBKBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1759234 | 0.76 | KDM4C (0.51) | IKBKBMEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL2808263 | 0.72 | KDM4E (0.42) | MEN1KMT2AALDH1A1PTGS2ESR2 | |
| SCHEMBL14104471 | 0.72 | CA12 (0.56) | MEN1KMT2AMAOAALDH1A1CA12 | |
| SCHEMBL29415441 | 0.72 | KDM4E (0.42) | MEN1KMT2AALDH1A1PTGS2ESR2 | |
| SCHEMBL3044443 | 0.71 | ESR2 (0.54) | MEN1KMT2AALDH1A1TSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581500-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5441949-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0581500-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |