Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790264 | 0.98 | PRNP (0.53) | PRNPKLK7ALDH1A1CYP2C9PTGES | |
| Lithium SCHEMBL790479 | 0.97 | PRNP (0.52) | PRNPKLK7ALDH1A1CYP2C9PTGES | |
| SCHEMBL11548569 | 0.85 | IKBKB (0.63) | PRNPKLK7ALDH1A1HPGDHSD17B10 | |
| Lithium Ion SCHEMBL790478 | 0.83 | PRNP (0.51) | PRNPKLK7ALDH1A1CYP2C9PTGES | |
| SCHEMBL8540585 | 0.81 | IKBKB (0.49) | ALDH1A1CYP2C9ALOX5HPGDCASP7 | |
| SCHEMBL2310035 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL30682029 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL2532082 | 0.79 | KMT2A (0.71) | ALDH1A1CYP2C9PTGESALOX5HPGD | |
| SCHEMBL28234137 | 0.79 | MEN1 (0.49) | PRNPALDH1A1CYP2C9PTGESALOX5 | |
| SCHEMBL790106 | 0.77 | ADORA2A (0.55) | PRNPKLK7ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |