SCHEMBL3044443

SCHEMBL3044443

Oc1ccc2nc3ccc(O)cc3cc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.54
ESR1 P03372 7/20 0.54
PDE3B Q13370 1/20 0.50
PDE3A Q14432 1/20 0.50
ALDH1A1 P00352 3/20 0.46
HPGD P15428 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ENPP2 Q13822 1/20 0.46
CYP1A2 P05177 1/20 0.46
GLA P06280 1/20 0.43
MAPT P10636 1/20 0.43
ACHE P22303 1/20 0.43
PLAU P00749 1/20 0.43
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4435489 0.89 ALDH1A1 (0.65) ESR2ESR1PDE3BPDE3AALDH1A1
SCHEMBL11059374 0.87 ESR1 (0.44) ESR2ESR1PDE3BPDE3AALDH1A1
SCHEMBL16500490 0.82 ESR1 (0.49) ESR2ESR1PDE3BPDE3AALDH1A1
SCHEMBL2368334 0.80 ALDH1A1 (0.54) ESR2ESR1ALDH1A1HPGDKDM4E
SCHEMBL14077239 0.80 ALDH1A1 (0.54) ESR2ESR1ALDH1A1HPGDKDM4E
SCHEMBL11059195 0.79 GUCY1B2 (0.54) ALDH1A1HPGDCYP1A2MAPTALOX15
SCHEMBL6430599 0.79 NQO2 (0.44) ESR2ESR1PDE3BPDE3AALDH1A1
SCHEMBL6240232 0.78 MEN1 (0.52) ESR2ESR1ALDH1A1HPGDKDM4E
SCHEMBL31296110 0.78 MEN1 (0.52) ESR2ESR1ALDH1A1HPGDKDM4E
SCHEMBL11055510 0.78 ESR1 (0.45) ESR2ESR1PDE3BPDE3ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243167-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2025-07-31 US disclosed
US-12275708-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2025-04-15 US disclosed
US-20240254088-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-08-01 US disclosed
US-11932603-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-03-19 US disclosed
US-20220227711-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2022-07-21 US disclosed
US-11332445-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2022-05-17 US disclosed
EP-1946108-B1 HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY SIEMENS HEALTHCARE DIAGNOSTICS (US) 2014-10-01 EP disclosed
US-7785904-B2 High quantum yield acridinium compounds and their uses in improving assay sensitivity SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2010-08-31 US disclosed
EP-1946108-A2 HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY Bayer Healthcare LLC (US) 2008-07-23 EP disclosed
US-20080014660-A1 High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity BAYER HEALTHCARE LLC 2008-01-17 US disclosed
US-7309615-B2 High quantum yield acridinium compounds and their uses in improving assay sensitivity SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) 2007-12-18 US disclosed
WO-2006130736-A2 HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS (US) 2006-12-07 WO disclosed
US-20050221390-A1 High quantum yield acridinium compounds and their uses in improving assay sensitivity BAYER HEALTHCARE LLC (US) 2005-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243167-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION ACR, HACD3, FCGR3B ESR2 1371/4885ESR1 169/4885PDE3B 2320/4885
US-20240254088-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION ACR, HACD3, FCGR3B ESR2 1371/4885ESR1 169/4885PDE3B 2320/4885
US-12275708-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission ACR, HACD3, FCGR3B ESR2 1371/4885ESR1 169/4885PDE3B 2320/4885
US-11332445-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission ACR, HACD3, FCGR3B ESR2 1371/4885ESR1 169/4885PDE3B 2320/4885
US-20220227711-A1 HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION ACR, HACD3, FCGR3B ESR2 1371/4885ESR1 169/4885PDE3B 2320/4885
US-11932603-B2 Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission ACR, HACD3, FCGR3B ESR2 1371/4885ESR1 169/4885PDE3B 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.