Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.65 |
| ▸ | CNR1 | P21554 | 3/20 | 0.60 |
| ▸ | CNR2 | P34972 | 3/20 | 0.60 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.60 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.54 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975149 | 0.85 | HTT (0.71) | HTTCNR1CNR2NR2F2TTBK1 | |
| SCHEMBL11846406 | 0.81 | KDM4E (0.63) | HTTSTAT1RXFP1PIK3CDPIK3R1 | |
| SCHEMBL31089994 | 0.81 | RXFP1 (0.56) | HTTSTAT1RXFP1PPARGNR2E3 | |
| SCHEMBL8542554 | 0.81 | HTT (0.72) | HTTCNR1CNR2NR2F2RXFP1 | |
| SCHEMBL23339883 | 0.79 | RXFP1 (0.60) | HTTSTAT1RXFP1PIK3CDPIK3R1 | |
| SCHEMBL19160676 | 0.78 | HTT (0.85) | HTTCNR1CNR2NR2F2TTBK1 | |
| SCHEMBL11857739 | 0.77 | HDAC1 (0.60) | HTTSTAT1RXFP1PIK3CDPIK3R1 | |
| SCHEMBL11855329 | 0.77 | HDAC1 (0.60) | HTTSTAT1RXFP1PIK3CDPIK3R1 | |
| SCHEMBL11849897 | 0.77 | HDAC1 (0.60) | HTTSTAT1RXFP1PIK3CDPIK3R1 | |
| SCHEMBL17994874 | 0.77 | DNMT3A (0.53) | HTTCNR1CNR2SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |