Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 10/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 8/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329145 | 0.89 | PTGS1 (0.50) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8538110 | 0.87 | TSHR (0.44) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8543897 | 0.86 | TTPA (0.42) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8539212 | 0.85 | CYP3A4 (0.47) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7335483 | 0.80 | USP2 (0.54) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL7336256 | 0.78 | MAPT (0.46) | CYP3A4TSHRACHEOPRM1MAPT | |
| Hydrochloric Acid SCHEMBL8814353 | 0.77 | MAPT (0.46) | CYP3A4TSHRACHEOPRM1MAPT | |
| SCHEMBL8544837 | 0.77 | CYP3A4 (0.52) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL7331438 | 0.77 | MAPT (0.45) | CYP3A4TSHRACHEOPRM1MAPT | |
| SCHEMBL9690451 | 0.76 | TSHR (0.49) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587499-B1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR (FR) | 1998-04-29 | — | — | EP | disclosed |
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |