Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | TTPA | P49638 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8814353 | 0.99 | MAPT (0.46) | MAPTLMNAUSP2CYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL7331438 | 0.98 | MAPT (0.45) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL7335483 | 0.90 | USP2 (0.54) | MAPTLMNAUSP2CYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL7335128 | 0.89 | ALOX5 (0.46) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL7558938 | 0.87 | ACHE (0.43) | MAPTLMNACYP2C9KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7336927 | 0.86 | HRH1 (0.44) | MAPTLMNAUSP2CYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL9287019 | 0.84 | MAPT (0.43) | MAPTLMNAUSP2CYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL7328648 | 0.80 | LMNA (0.56) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL8540688 | 0.78 | PTGS1 (0.45) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL7329145 | 0.78 | PTGS1 (0.50) | LMNAACHECYP3A4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646149-A | N,N*-SUBSTITUTED PIPERAZINE DERIVATIVES; VISION DEFECTS | ALCON LABORATORIES, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1995015958-A1 | COMPOUNDS HAVING BOTH POTENT CALCIUM ANTAGONIST AND ANTIOXIDANT ACTIVITY AND USE THEREOF AS CYTOPROTECTIVE AGENTS | ALCON LABORATORIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |