Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305666 | 0.82 | POLB (0.48) | POLBKMT2AMEN1CASP3ALDH1A1 | |
| SCHEMBL8545658 | 0.79 | POLB (0.44) | POLBKMT2AMEN1CASP3CES1 | |
| SCHEMBL1966590 | 0.78 | POLB (0.45) | POLBSMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL8543267 | 0.78 | CES1 (0.42) | POLBSMN1; SMN2KMT2AMEN1CASP3 | |
| SCHEMBL8303714 | 0.78 | LMNA (0.43) | POLBKMT2ACASP3NPC1ALDH1A1 | |
| SCHEMBL8307356 | 0.76 | GRM1 (0.42) | POLBSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL8446968 | 0.76 | ALDH1A1 (0.47) | POLBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8539713 | 0.75 | POLB (0.41) | POLBKMT2AMEN1CASP3HTT | |
| SCHEMBL8880732 | 0.75 | NPC1 (0.51) | SMN1; SMN2KMT2AMEN1CASP3RPS6KA2 | |
| SCHEMBL8545476 | 0.74 | SLC18A3 (0.40) | POLBSMN1; SMN2KMT2ACASP3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648764-B1 | N-(substituted amino)pyrrole derivatives, preparation process thereof, and herbicidal compositions | KUREHA CHEMICAL IND CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5612287-A | N-(substituted amino) pyrrole derivatives preparation process thereof, and herbicidal compositions | KUREHA KAGAKU KOGYO K.K. (JP) | 1997-03-18 | — | — | US | disclosed |
| US-5604178-A | N-(substituted amino)pyrrole derivatives, and herbicidal compositions | KUREHA KAGAKU KOGYO K.K. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0648764-A1 | N-(substituted amino)pyrrole derivatives, preparation process thereof, and herbicidal compositions | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-04-19 | — | — | EP | disclosed |