SCHEMBL8540709

SCHEMBL8540709

CC(Cl)=NN=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 5/20 0.38
ENPP3 O14638 4/20 0.38
ENPP2 Q13822 3/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
CXCR2 P25025 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CXCR1 P25024 1/20 0.36
PSEN1 P49768 1/20 0.36
PSEN2 P49810 1/20 0.36
APH1B Q8WW43 1/20 0.36
NCSTN Q92542 1/20 0.36
APH1A Q96BI3 1/20 0.36
PSENEN Q9NZ42 1/20 0.36
PPARA Q07869 2/20 0.36
FABP2 P12104 1/20 0.36
PPARG P37231 1/20 0.36
SLC22A12 Q96S37 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10969416 0.84 GAA (0.38) ENPP1ENPP3ENPP2CXCR2ALDH1A1
SCHEMBL9175055 0.84 ENPP1 (0.39) ENPP1ENPP3ENPP2CXCR2ALDH1A1
SCHEMBL11231034 0.84 GAA (0.38) ENPP1ENPP3ENPP2CXCR2ALDH1A1
SCHEMBL9565985 0.83 CYP11B1 (0.34) ENPP1ENPP3ENPP2CA1CA2
SCHEMBL9566100 0.83 ALDH1A1 (0.35) ENPP1ENPP3ENPP2CA1CA2
SCHEMBL7108334 0.82 CA1 (0.46) ENPP1ENPP3ENPP2CA1CA2
SCHEMBL8533900 0.82 CA1 (0.46) ENPP1ENPP3ENPP2CA1CA2
SCHEMBL9565958 0.81 DRD2 (0.35) ENPP1ENPP3ENPP2CA1CA2
SCHEMBL11211740 0.81 ENPP1 (0.38) ENPP1ENPP3ENPP2CA1CA2
SCHEMBL11211743 0.81 ENPP1 (0.38) ENPP1ENPP3ENPP2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0662472-B1 Hydrazone derivates as pesticides CIBA GEIGY AG (CH) 1998-03-11 EP disclosed
EP-0662472-A1 Hydrazone derivates as pesticides CIBA-GEIGY AG (CH) 1995-07-12 EP disclosed
EP-0566534-A1 Derivatives of benzophenone CIBA-GEIGY AG (CH) 1993-10-20 EP disclosed