Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537576 | 0.79 | CSNK1A1 (0.49) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| Hydrochloric Acid SCHEMBL20204146 | 0.77 | CSNK1A1 (0.47) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8537087 | 0.75 | CSNK1A1 (0.45) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8537580 | 0.74 | CSNK1A1 (0.44) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL17304239 | 0.73 | CSNK1A1 (0.53) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8540973 | 0.72 | ADRA1A (0.54) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8535959 | 0.72 | CSNK1A1 (0.42) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8540945 | 0.71 | CSNK1A1 (0.42) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8537574 | 0.71 | CSNK1A1 (0.47) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 | |
| SCHEMBL8539281 | 0.70 | MC4R (0.38) | ADRA1ACSNK1A1TYRO3DYRK1BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |