Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038254 | 0.92 | TBXAS1 (0.55) | TBXAS1TMEM97SIGMAR1LTA4HKMT2A | |
| SCHEMBL8545842 | 0.81 | CCR3 (0.56) | — | |
| SCHEMBL8544146 | 0.81 | GRIN2B (0.56) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL10370478 | 0.80 | TBXAS1 (1.00) | TBXAS1LTA4HKMT2ANOS1KDM4E | |
| SCHEMBL8538300 | 0.80 | GRIN2B (0.54) | SIGMAR1 | |
| SCHEMBL8693762 | 0.79 | TMEM97 (0.68) | TMEM97SIGMAR1LTA4HKMT2A | |
| Hydrochloric Acid SCHEMBL9996050 | 0.79 | TBXAS1 (0.97) | TBXAS1LTA4HKMT2ANOS1KDM4E | |
| SCHEMBL8545375 | 0.79 | SIGMAR1 (0.59) | SIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL8546852 | 0.79 | GRIN2B (0.53) | TBXAS1SIGMAR1 | |
| SCHEMBL8695655 | 0.78 | TMEM97 (0.66) | TMEM97SIGMAR1LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |