Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540915 | 1.00 | LMNA (0.49) | LMNAHTTRIPK1MAPK1ALDH1A1 | |
| SCHEMBL4338097 | 0.86 | MAPK1 (0.45) | LMNAHTTRIPK1MAPK1GPR88 | |
| SCHEMBL1720120 | 0.83 | MAPK1 (0.43) | LMNAHTTRIPK1MAPK1ALDH1A1 | |
| SCHEMBL1720123 | 0.83 | MAPK1 (0.43) | LMNAHTTRIPK1MAPK1ALDH1A1 | |
| SCHEMBL4536126 | 0.83 | MAPK1 (0.43) | LMNAHTTRIPK1MAPK1ALDH1A1 | |
| SCHEMBL4337140 | 0.82 | MAPK1 (0.47) | LMNAHTTRIPK1MAPK1GPR88 | |
| SCHEMBL1953208 | 0.82 | MAPK1 (0.48) | LMNAHTTRIPK1MAPK1ALDH1A1 | |
| SCHEMBL16830004 | 0.79 | LMNA (0.51) | LMNAHTTMAPK1ALDH1A1GPR88 | |
| SCHEMBL4341623 | 0.79 | GPR88 (0.47) | LMNAHTTRIPK1MAPK1GPR88 | |
| SCHEMBL16830003 | 0.79 | LMNA (0.51) | LMNAHTTMAPK1ALDH1A1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801249-A | Chiral auxiliaries | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 1998-09-01 | — | — | US | disclosed |