Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 9/20 | 0.42 |
| ▸ | BCHE | P06276 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539212 | 0.90 | CYP3A4 (0.47) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8544837 | 0.90 | CYP3A4 (0.52) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9266621 | 0.88 | CYP3A4 (0.46) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9690307 | 0.88 | PTGS1 (0.53) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8542945 | 0.85 | TTPA (0.44) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8538110 | 0.82 | TSHR (0.44) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8543465 | 0.79 | CYP3A4 (0.45) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9690175 | 0.77 | TSHR (0.50) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8538265 | 0.77 | CYP3A4 (0.49) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL8538881 | 0.77 | PTGS1 (0.49) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587499-B1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR (FR) | 1998-04-29 | — | — | EP | disclosed |
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |