Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.74 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545462 | 0.91 | ITGB3 (0.67) | ITGB3ITGA2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6953119 | 0.89 | ITGB3 (0.78) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL6954012 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BCYP2D6OPRK1MCHR1 | |
| SCHEMBL6951251 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL6958047 | 0.86 | ITGB3 (0.73) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL6957424 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BCYP2D6NPC1PKM | |
| SCHEMBL6496087 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL6496092 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL6951962 | 0.84 | ITGB3 (0.70) | ITGB3ITGA2BRAB9ASMN1; SMN2 | |
| SCHEMBL6957669 | 0.84 | ITGB3 (0.86) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804431-A4 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | LILLY CO ELI (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0804431-A1 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-11-05 | — | — | EP | disclosed |