Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959301 | 0.92 | ITGB3 (0.56) | ITGB3ITGA2BRAB9ANPC1MEN1 | |
| SCHEMBL8541193 | 0.91 | ITGB3 (0.74) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6957424 | 0.86 | ITGB3 (0.59) | ITGB3ITGA2BRAB9ANPC1MEN1 | |
| SCHEMBL6958047 | 0.85 | ITGB3 (0.73) | ITGB3ITGA2B | |
| SCHEMBL6951251 | 0.85 | ITGB3 (0.75) | ITGB3ITGA2B | |
| SCHEMBL6953119 | 0.85 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL6954012 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BRAB9ANPC1MEN1 | |
| SCHEMBL8545467 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2BRAB9ANPC1MEN1 | |
| SCHEMBL6951962 | 0.83 | ITGB3 (0.70) | ITGB3ITGA2BRAB9AMEN1KMT2A | |
| SCHEMBL6948904 | 0.83 | ITGB3 (0.69) | ITGB3ITGA2BRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804431-A4 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | LILLY CO ELI (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0804431-A1 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-11-05 | — | — | EP | disclosed |