SCHEMBL8541302

SCHEMBL8541302

CCCCCCCCCCC1Cc2ccc(-c3ncc(OCCCc4ccccc4)cn3)cc2C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.40
KDM4E B2RXH2 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HSD17B10 Q99714 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
HRH3 Q9Y5N1 2/20 0.39
NAAA Q02083 1/20 0.38
RARB P10826 1/20 0.38
NPC1 O15118 3/20 0.36
CNR2 P34972 2/20 0.36
CNR1 P21554 1/20 0.36
MAOA P21397 4/20 0.36
MAOB P27338 4/20 0.36
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8553157 0.90 RAB9A (0.42) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8552026 0.85 RAB9A (0.43) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8556698 0.85 RAB9A (0.36) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL7118001 0.84 RARB (0.50) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8552162 0.84 RARB (0.50) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8552427 0.84 RARB (0.50) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8557226 0.83 MAPT (0.50) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8553224 0.82 NPC1 (0.45) RAB9AKDM4ESMN1; SMN2HSD17B10ALDH1A1
SCHEMBL8558587 0.79 FYN (0.36) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1
SCHEMBL8551722 0.78 FYN (0.40) RAB9AKDM4ESMN1; SMN2HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640677-B1 Mesomorphic compound, liquid crystal composition containing the compound, liquid crystal device using the composition, liquid crystal apparatus and display method CANON KK (JP) 1998-10-28 EP disclosed
US-5462694-A Improved high speed response CANON KABUSHIKI KAISHA (JP) 1995-10-31 US disclosed
EP-0640677-A1 Mesomorphic compound, liquid crystal composition containing the compound, liquid crystal device using the composition, liquid crystal apparatus and display method CANON KABUSHIKI KAISHA (JP) 1995-03-01 EP disclosed