Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553157 | 0.95 | RAB9A (0.42) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8553224 | 0.90 | NPC1 (0.45) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8556698 | 0.88 | RAB9A (0.36) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8541302 | 0.85 | RAB9A (0.40) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8558587 | 0.84 | FYN (0.36) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8552877 | 0.84 | KDM4E (0.48) | RAB9AKDM4EMAPTRARBALDH1A1 | |
| SCHEMBL8542748 | 0.81 | FYN (0.40) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8551722 | 0.81 | FYN (0.40) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8555728 | 0.81 | CYP3A4 (0.32) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9157252 | 0.81 | NPC1 (0.56) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |