SCHEMBL854154

SCHEMBL854154

O=[N+]([O-])c1cccc(S(=O)(=O)CCO)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
GAA P10253 2/20 0.62
HTT P42858 1/20 0.62
CA2 P00918 3/20 0.58
CA5A P35218 1/20 0.58
MMP2 P08253 2/20 0.58
CA1 P00915 1/20 0.58
MMP1 P03956 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58
MEN1 O00255 1/20 0.56
F2 P00734 2/20 0.54
PRSS1 P07477 2/20 0.54
PRSS2 P07478 2/20 0.54
PRSS3 P35030 2/20 0.54
PKM P14618 2/20 0.53
CYP19A1 P11511 1/20 0.51
LMNA P02545 2/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28121364 0.91 KMT2A (0.58) KMT2AGAAHTTCA2CA5A
SCHEMBL27950143 0.90 KMT2A (0.70) KMT2AGAAHTTCA2CA5A
SCHEMBL9550616 0.84 PKM (0.60) KMT2ACA2MMP2CA1MMP1
SCHEMBL681532 0.84 KMT2A (0.62) KMT2AGAAHTTCA2CA5A
SCHEMBL7031854 0.84 KMT2A (0.62) KMT2AGAAHTTCA2CA5A
SCHEMBL2876686 0.81 KMT2A (0.68) KMT2AGAAHTTCA2CA5A
SCHEMBL4161667 0.81 KMT2A (0.58) KMT2AGAAHTTCA2CA5A
SCHEMBL15272469 0.81 KMT2A (0.58) KMT2AGAAHTTCA2CA5A
SCHEMBL9340091 0.81 CA2 (0.58) KMT2ACA2CA5AMMP2CA1
SCHEMBL11077621 0.80 KMT2A (0.57) KMT2AGAAHTTCA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117702137-A Method for preparing m- (beta-hydroxyethyl sulfone) aniline by electrolytic reduction of m- (beta-hydroxyethyl sulfone) nitrobenzene 华东理工大学 2024-03-15 CN claimed
CN-112958114-A Raney nickel catalyst for hydrogenation of aromatic nitro compound in fixed bed and application thereof 大连理工大学 2021-06-15 CN claimed
CN-111072527-A Preparation method of dye intermediate 3- (β -hydroxyethyl sulfonyl) -nitrobenzene 荆门市丽康源纺织科技有限公司 2020-04-28 CN claimed
EP-3965738-B1 METHOD FOR PRODUCTION OF LIPOSOMES UNIV DO MINHO (PT) 2025-08-06 EP disclosed
CN-115197107-B Meta-ester chlorosulfonation synthesis method with high yield and low consumption of sulfonating agent 湖北丽康源化工有限公司 2024-07-30 CN disclosed
CN-117702137-A Method for preparing m- (beta-hydroxyethyl sulfone) aniline by electrolytic reduction of m- (beta-hydroxyethyl sulfone) nitrobenzene 华东理工大学 2024-03-15 CN disclosed
CN-117702137-A Method for preparing m- (beta-hydroxyethyl sulfone) aniline by electrolytic reduction of m- (beta-hydroxyethyl sulfone) nitrobenzene 华东理工大学 2024-03-15 CN disclosed
CN-117702137-A Method for preparing m- (beta-hydroxyethyl sulfone) aniline by electrolytic reduction of m- (beta-hydroxyethyl sulfone) nitrobenzene 华东理工大学 2024-03-15 CN disclosed
CN-115197107-A High-yield low-sulfonating agent consumption m-ester chlorosulfonation synthesis method 湖北丽康源化工有限公司 2022-10-18 CN disclosed
US-20220241203-A1 METHOD FOR PRODUCTION OF LIPOSOMES UNIVERSIDADE DO MINHO (PT) 2022-08-04 US disclosed
CN-112958114-A Raney nickel catalyst for hydrogenation of aromatic nitro compound in fixed bed and application thereof 大连理工大学 2021-06-15 CN disclosed
EP-0841323-A2 Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-13 EP disclosed
US-5622137-A FOR USE IN TESTING COOKED FOODS TRANS WORLD SERVICES (US) 1997-04-22 US disclosed
EP-0426536-B1 Production of aromatic amines SUMITOMO CHEMICAL CO (JP) 1994-12-14 EP disclosed
US-5315040-A Reduction of nitro compounds using ruthenium catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-24 US disclosed
US-5112997-A Reduction of nitroanthraquinones with carbon monoxide and a rhodium catalyst SUMITOMO CHEMICAL CO., LTD. (JP) 1992-05-12 US disclosed
EP-0426536-A1 Production of aromatic amines SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-08 EP disclosed
US-4760183-A Process for the preparation of aromatic dialkylamines HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
EP-0212607-A1 Process for the production of halophenyl-hydroxyethyl sulphides and their oxidation products HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed
EP-0085025-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-08-03 EP disclosed