⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443775 | 0.72 | TSHR (0.53) | — | |
| SCHEMBL441930 | 0.72 | — | — | |
| Acetic Acid SCHEMBL28586247 | 0.69 | TSHR (0.88) | — | |
| Bicarbonate SCHEMBL11023772 | 0.69 | TSHR (0.88) | — | |
| Acetic Acid SCHEMBL1024317 | 0.69 | TSHR (0.88) | — | |
| Benzene SCHEMBL8104016 | 0.67 | TSHR (0.82) | — | |
| SCHEMBL21247 | 0.67 | TSHR (0.47) | — | |
| SCHEMBL19193 | 0.67 | — | — | |
| SCHEMBL21064874 | 0.67 | TSHR (1.00) | — | |
| SCHEMBL10196614 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573415-B | Process for producing nanoparticles | 3M INNOVATIVE PROPERTIES CO | 2013-08-14 | — | — | CN | claimed |
| CN-101573415-A | Process for producing nanoparticles | 3M INNOVATIVE PROPERTIES CO (US) | 2009-11-04 | — | — | CN | claimed |
| US-6790892-B1 | MERCAPTAN-CONTAINING HEAT STABILIZER COMPOSITION SUBSTANTIALLY FREE FROM OFFENSIVE ODOR | ROHM AND HAAS COMPANY | 2004-09-14 | — | — | US | claimed |
| US-6743840-B1 | HEAT STABILIZER; ODORLESS; DEGRADATION PRODUCTS OF A BLOCKED MERCAPTAN | ROHM AND HAAS COMPANY | 2004-06-01 | — | — | US | claimed |
| US-20030216493-A1 | Latent mercaptans as multi-functional additives for halogen-containing polymer compositions | PMC CINCINNATI, INC. | 2003-11-20 | — | — | US | claimed |
| US-6548707-B1 | Deodorizing; heat and oxidation resistance; stabilizers | ROHM AND HAAS COMPANY | 2003-04-15 | — | — | US | claimed |
| US-6537466-B1 | Odor free heat stabilizers; also serve as intermediates for antioxidants, antimicrobial agents, photostabilizers, and primary heat stabilizers | ROHM AND HAAS COMPANY | 2003-03-25 | — | — | US | claimed |
| US-20020068780-A1 | LATENT MERCAPTANS AS MULTI-FUNCTIONAL ADDITIVES FOR HALOGEN-CONTAINING POLYMER COMPOSITIONS | PMC CINCINNATI, INC. | 2002-06-06 | — | — | US | claimed |
| EP-2432768-B1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-9533978-B2 | Pyrimidine derivatives and their use in the treatment of cancer and further diseases | SUMITOMO DAINIPPON PHARMA CO., LTD (JP) | 2017-01-03 | — | — | US | disclosed |
| US-20150080396-A1 | Novel Pyrimidine Derivatives and Their Use in the Treatment of Cancer and Further Diseases | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2015-03-19 | — | — | US | disclosed |
| CN-104302644-A | Thiazolecarboxamide derivatives and methods of use thereof | NIHON NOHYAKU CO LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-104046131-A | Ink for inkjet, ink cartridge using the ink, inkjet recorder and ink recorded matter | RICOH CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-101573415-B | Process for producing nanoparticles | 3M INNOVATIVE PROPERTIES CO | 2013-08-14 | — | — | CN | disclosed |
| CN-102993828-A | Ink for inkjet recording, inkjet recording method, inkjet recording device, and ink recording material | RICOH CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-20120122867-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | ASTRAZENECA UK LIMITED (GB) | 2012-05-17 | — | — | US | disclosed |
| EP-2432768-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | AstraZeneca AB (SE) | 2012-03-28 | — | — | EP | disclosed |
| CN-1809570-B | [1,2,4] triazolo [1,5-a ] pyrimidin-2-ylurea derivatives and uses thereof | NIPPON KAYAKU KK | 2011-06-22 | — | — | CN | disclosed |
| WO-2010133885-A1 | NOVEL PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND FURTHER DISEASES | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | WO | disclosed |
| CN-101573415-A | Process for producing nanoparticles | 3M INNOVATIVE PROPERTIES CO (US) | 2009-11-04 | — | — | CN | disclosed |