Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.82 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28259736 | 0.97 | TSHR (0.78) | TSHRPDCD1CD274CA12CA1 | |
| Acetic Acid SCHEMBL1024317 | 0.91 | TSHR (0.88) | TSHRPDCD1CD274CA12CA1 | |
| Acetic Acid SCHEMBL28586247 | 0.91 | TSHR (0.88) | TSHRPDCD1CD274CA12CA1 | |
| Bicarbonate SCHEMBL11023772 | 0.91 | TSHR (0.88) | TSHRPDCD1CD274CA12CA1 | |
| SCHEMBL21064874 | 0.91 | TSHR (1.00) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL19193 | 0.91 | — | — | |
| SCHEMBL3495565 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL584909 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL5086843 | 0.88 | — | — | |
| SCHEMBL1278490 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033006-B | Preparation method of diaryl ketone | 长沙理工大学 | 2018-12-18 | — | — | CN | claimed |
| CN-107033006-A | Preparation method of diaryl ketone | 长沙理工大学 | 2017-08-11 | — | — | CN | claimed |
| EP-3368513-B1 | PROCESS FOR THE SYNTHESIS OF PIRFENIDONE | PROCOS SPA (IT) | 2021-04-14 | — | — | EP | disclosed |
| US-10472325-B2 | Process for the synthesis of pirfenidone | PROCOS S.P.A. (IT) | 2019-11-12 | — | — | US | disclosed |
| US-20180319747-A1 | PROCESS FOR THE SYNTHESIS OF PIRFENIDONE | PROCOS S.P.A. (IT) | 2018-11-08 | — | — | US | disclosed |
| EP-3368513-A1 | PROCESS FOR THE SYNTHESIS OF PIRFENIDONE | Procos S.p.A. (IT) | 2018-09-05 | — | — | EP | disclosed |
| CN-107141879-A | One kind print paper money ink | 北京知乎科技有限责任公司 | 2017-09-08 | — | — | CN | disclosed |
| WO-2017072216-A1 | PROCESS FOR THE SYNTHESIS OF PIRFENIDONE | PROCOS S.P.A. (IT) | 2017-05-04 | — | — | WO | disclosed |
| US-6160194-A | Soil decontamination using ferric chelates and peroxide | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 2000-12-12 | — | — | US | disclosed |
| US-5232484-A | Aqueous acid solution; mineralization; absence of large concentrations of organic solvents, chloride and sulfate | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-4060688-A | Cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319747-A1 | PROCESS FOR THE SYNTHESIS OF PIRFENIDONE | PNPO, NUDT1, PIR | TSHR 2894/4885PDCD1 348/4885CD274 1611/4885 |
| US-10472325-B2 | Process for the synthesis of pirfenidone | PNPO, NUDT1, PIR | TSHR 2894/4885PDCD1 348/4885CD274 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.