Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | CCNC | P24863 | 4/20 | 0.57 |
| ▸ | CDK8 | P49336 | 4/20 | 0.57 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.57 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283269 | 0.89 | HTT (0.76) | HTTLMNASMN1; SMN2MAPK1EGFR | |
| SCHEMBL157421 | 0.87 | NFKB1 (0.63) | HTTLMNAMAPK1EGFRAPP | |
| SCHEMBL29350229 | 0.87 | NFKB1 (0.63) | HTTLMNAMAPK1EGFRAPP | |
| SCHEMBL8543007 | 0.87 | HTT (0.77) | HTTLMNASMN1; SMN2MAPK1EGFR | |
| SCHEMBL8542891 | 0.84 | HTT (0.54) | HTTLMNAMAPK1EGFRAPP | |
| SCHEMBL28530926 | 0.83 | CCNC (0.57) | HTTLMNAMAPK1EGFRAPP | |
| SCHEMBL8545770 | 0.82 | HTT (0.82) | HTTLMNASMN1; SMN2MAPK1EGFR | |
| SCHEMBL8547638 | 0.79 | MAPK1 (0.55) | HTTLMNASMN1; SMN2MAPK1EGFR | |
| SCHEMBL8548572 | 0.79 | EGFR (0.71) | HTTLMNASMN1; SMN2MAPK1EGFR | |
| SCHEMBL8542554 | 0.79 | HTT (0.72) | HTTLMNASMN1; SMN2MAPK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |