Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832295 | 0.93 | TDP1 (0.48) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL10809043 | 0.82 | ALDH1A1 (0.46) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL3929771 | 0.78 | LCK (0.40) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL14580636 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL8930119 | 0.78 | TDP1 (0.49) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL1131162 | 0.77 | TDP1 (0.44) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL18359691 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TDP1EYA2APPACE | |
| SCHEMBL8541736 | 0.75 | LMNA (0.46) | ALDH1A1TDP1ALOX15CYP2C19TSHR | |
| SCHEMBL3973204 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNAMEN1MAPT | |
| SCHEMBL24129407 | 0.75 | PRKCI (0.66) | ALDH1A1TDP1PRKCIALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497356-B1 | Compositions and method for soft tissue tumors | DOW CHEMICAL CO (US) | 1998-08-12 | — | — | EP | disclosed |
| WO-1992013826-A1 | COMPOSITIONS AND METHOD FOR SOFT TISSUE TUMORS | THE DOW CHEMICAL COMPANY (US) | 1992-08-20 | — | — | WO | disclosed |