Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543738 | 0.91 | TBXAS1 (0.51) | TBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8541082 | 0.84 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL8543882 | 0.84 | TBXAS1 (0.67) | TBXAS1TBXA2R | |
| SCHEMBL8541824 | 0.79 | TBXAS1 (0.67) | TBXAS1TBXA2R | |
| SCHEMBL8544224 | 0.78 | TBXAS1 (0.41) | TBXAS1MEN1KMT2A | |
| SCHEMBL8538814 | 0.77 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL8310212 | 0.77 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL8542531 | 0.76 | TBXAS1 (0.50) | TBXAS1 | |
| SCHEMBL8538700 | 0.76 | TBXAS1 (0.55) | TBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL8538829 | 0.73 | TBXAS1 (0.59) | TBXAS1TBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |