Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500395 | 0.95 | HIF1A (0.39) | HIF1ATAS1R3TAS1R1MAPTSMN1; SMN2 | |
| SCHEMBL8538331 | 0.90 | HIF1A (0.37) | HIF1AMAPTLMNAL3MBTL1 | |
| SCHEMBL7505113 | 0.86 | PLK1 (0.39) | TAS1R3TAS1R1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7494764 | 0.85 | HIF1A (0.40) | HIF1AMAPTFAAH | |
| SCHEMBL7501618 | 0.83 | HIF1A (0.40) | HIF1ALMNAFAAH | |
| SCHEMBL7495599 | 0.83 | ALDH1A1 (0.38) | MAPTRAB9ALMNAPLK1MEN1 | |
| SCHEMBL7130516 | 0.82 | HIF1A (0.42) | HIF1AMAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7742093 | 0.80 | HIF1A (0.42) | HIF1AMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL7502694 | 0.79 | HIF1A (0.42) | HIF1ALMNA | |
| SCHEMBL7494944 | 0.78 | HIF1A (0.34) | HIF1AMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |