SCHEMBL854412

SCHEMBL854412

c1ccc(-c2cccc(-c3ccccc3)c2Oc2c(-c3ccccc3)cccc2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 2/20 0.46
HPGD P15428 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CYP2A6 P11509 1/20 0.46
NCOA1 Q15788 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
BACE1 P56817 1/20 0.42
DPP4 P27487 1/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
HNF4A P41235 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9780765 0.87 LTA4H (0.50) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL8773051 0.84 ALDH1A1 (0.60) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL258076 0.84 PDCD1 (0.47) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL29145892 0.84 ALDH1A1 (0.60) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL3370607 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL22981733 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL3370610 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL21646330 0.79 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL13385087 0.79 PDE4B (0.48) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL10304844 0.79 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPK1HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111448256-B Thermoplastic resin composition 株式会社LG化学 2023-03-14 CN claimed
CN-111448256-A Thermoplastic resin composition 株式会社LG化学 2020-07-24 CN claimed
CN-122011436-A Polyphenyl ether filler, and preparation method and application thereof 上海安谱实验科技股份有限公司 2026-05-12 CN disclosed
CN-117677668-A Thermoplastic elastomer composition and molded article formed from the same 可乐丽塑料株式会社 2024-03-08 CN disclosed
CN-117120548-A Polycarbonate resin composition and molded article 出光兴产株式会社 2023-11-24 CN disclosed
EP-3020753-B1 FLAME RETARDANT FIBRE-MATRIX SEMIFINISHED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-08-16 EP disclosed
CN-116348529-A Polycarbonate resin composition and circuit molded article for communication device 帝人株式会社 2023-06-27 CN disclosed
EP-4177311-A1 USE OF POLYAMIDE 6 LANXESS Performance Materials GmbH (DE) 2023-05-10 EP disclosed
CN-116063827-A Use of polyamide 6 朗盛性能材料有限责任公司 2023-05-05 CN disclosed
US-20230132793-A1 Use of polyamide 6 LANXESS Performance Materials GmbH (DE) 2023-05-04 US disclosed
CN-111448256-B Thermoplastic resin composition 株式会社LG化学 2023-03-14 CN disclosed
EP-1113517-B1 Polymer electrolyte and method for producing the same SUMITOMO CHEMICAL CO (JP) 2007-09-12 EP disclosed
US-20060280999-A1 Polymer electrolyte fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED 2006-12-14 US disclosed
EP-1626453-A2 Polymer electrolyte fuel cell Sumitomo Chemical Company, Limited (JP) 2006-02-15 EP disclosed
US-20030044669-A1 Polymer electrolyte membrane and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED 2003-03-06 US disclosed
EP-1274147-A2 Polymer electrolyte membrane and fuel cell SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-08 EP disclosed
EP-0275141-B1 EPOXY CONTAINING IMPACT MODIFIERS FOR THERMOPLASTIC RESINS COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1993-07-28 EP disclosed
US-5008342-A Modified rubber CITIBANK, N.A., AS COLLATERAL AGENT 1991-04-16 US disclosed
EP-0275141-A2 Epoxy containing impact modifiers for thermoplastic resins COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1988-07-20 EP disclosed
EP-0274744-A2 Epoxy containing impact modifiers for thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1988-07-20 EP disclosed