Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 13/20 | 0.42 |
| ▸ | PLG | P00747 | 12/20 | 0.42 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547835 | 0.83 | FKBP1A (0.47) | PLAUPLGF10PLATF2 | |
| SCHEMBL8541691 | 0.79 | POLB (0.52) | — | |
| SCHEMBL8541688 | 0.79 | POLB (0.52) | — | |
| SCHEMBL8542714 | 0.79 | RAB9A (0.39) | F2 | |
| SCHEMBL8542717 | 0.79 | RAB9A (0.39) | F2 | |
| SCHEMBL8542711 | 0.79 | RAB9A (0.39) | F2 | |
| SCHEMBL8548046 | 0.75 | RAB9A (0.36) | F2 | |
| SCHEMBL8548038 | 0.75 | RAB9A (0.36) | F2 | |
| SCHEMBL5961946 | 0.73 | EPHX2 (0.51) | EPHX2 | |
| SCHEMBL8546861 | 0.72 | HTT (0.46) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610744-B1 | Sulfonamide aminomethylene derivatives as immunosuppressants | BAYER AG (US) | 1998-11-04 | — | — | EP | claimed |