Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 4/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544963 | 0.83 | CARM1 (0.40) | LMNAALDH1A1 | |
| SCHEMBL8544587 | 0.83 | LMNA (0.35) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8546372 | 0.83 | LMNA (0.35) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8547535 | 0.83 | LMNA (0.35) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8544380 | 0.82 | KMT2A (0.40) | MEN1KMT2ALMNAALOX15CRHBP | |
| SCHEMBL8543127 | 0.74 | LMNA (0.39) | MEN1KMT2ALMNAATMPIK3C3 | |
| SCHEMBL8544766 | 0.73 | LMNA (0.36) | LMNAOPRD1ATMPIK3C3ATR | |
| SCHEMBL6219487 | 0.72 | HDAC3 (0.41) | SMYD3 | |
| SCHEMBL8543536 | 0.72 | LMNA (0.36) | KMT2ALMNAALDH1A1OPRD1ATM | |
| SCHEMBL5766655 | 0.72 | RARB (0.41) | ALDH1A1MAPTSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |