Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543127 | 0.85 | LMNA (0.39) | LMNAATMPIK3C3ATRPRKDC | |
| SCHEMBL8543294 | 0.84 | CARM1 (0.40) | — | |
| SCHEMBL8547535 | 0.82 | LMNA (0.35) | LMNAOPRD1CASRATMPIK3C3 | |
| SCHEMBL8546372 | 0.82 | LMNA (0.35) | LMNAOPRD1CASRATMPIK3C3 | |
| SCHEMBL8544587 | 0.82 | LMNA (0.35) | LMNAOPRD1CASRATMPIK3C3 | |
| SCHEMBL8544380 | 0.82 | KMT2A (0.40) | LMNAOPRD1ABHD6DAGLA | |
| SCHEMBL8543536 | 0.78 | LMNA (0.36) | LMNAOPRD1CASRATMPIK3C3 | |
| SCHEMBL8544376 | 0.73 | MEN1 (0.37) | LMNAOPRD1ATMPIK3C3ATR | |
| SCHEMBL8543860 | 0.71 | LMNA (0.37) | LMNACASR | |
| SCHEMBL8544706 | 0.70 | GRIN2B (0.40) | LMNACASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |