SCHEMBL8544442

SCHEMBL8544442

O=C(NCCO)c1c(I)c(NC(=O)N(CC(O)CO)c2c(I)c(C(=O)NCCO)c(I)c(C(=O)NCC(O)CO)c2I)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.66
HIF1A Q16665 1/20 0.66
LMNA P02545 3/20 0.63
EGFR P00533 1/20 0.30
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380586 0.92 LMNA (0.56) CYP2C19HIF1ALMNA
SCHEMBL8381823 0.89 CYP2C19 (0.52) CYP2C19HIF1ALMNA
SCHEMBL8377059 0.87 CYP2C19 (0.70) CYP2C19HIF1ALMNAEGFRSRC
SCHEMBL8378485 0.87 LMNA (0.60) CYP2C19HIF1ALMNAEGFRSRC
Ioxilan SCHEMBL8844906 0.86 CYP2C19 (0.88) CYP2C19HIF1ALMNAEGFRSRC
SCHEMBL9231788 0.86 CYP2C19 (0.69) CYP2C19HIF1ALMNAEGFRSRC
Ioxilan SCHEMBL25634 0.86 CYP2C19 (0.88) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL4409596 0.86 CYP2C19 (0.88) CYP2C19HIF1ALMNAEGFRSRC
SCHEMBL8380584 0.85 LMNA (0.52) CYP2C19HIF1ALMNAEGFRSRC
SCHEMBL8743127 0.84 LMNA (0.57) CYP2C19HIF1ALMNAEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782565-B1 IODINATED X-RAY-CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1999-04-07 EP disclosed