Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.88 |
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ioxilan SCHEMBL25634 | 1.00 | CYP2C19 (0.88) | CYP2C19HIF1ALMNAEGFRSRC | |
| Ioxilan SCHEMBL8844906 | 1.00 | CYP2C19 (0.88) | CYP2C19HIF1ALMNAEGFRSRC | |
| Ioxilan SCHEMBL8863793 | 0.98 | CYP2C19 (0.84) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL966725 | 0.98 | LMNA (0.88) | CYP2C19HIF1ALMNAEGFRSRC | |
| SCHEMBL11147513 | 0.95 | CYP2C19 (0.79) | CYP2C19HIF1ALMNA | |
| SCHEMBL966699 | 0.94 | LMNA (0.78) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL37920 | 0.94 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL31722694 | 0.94 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL26501 | 0.94 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL8844889 | 0.94 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088860-A2 | A METHOD OF PREVENTING CONTRAST-INDUCED NEPHROPATHY | INOTEK PHARMACEUTICALS CORPORATION (US) | 2009-07-16 | — | — | WO | claimed |
| WO-2009088860-A2 | A METHOD OF PREVENTING CONTRAST-INDUCED NEPHROPATHY | INOTEK PHARMACEUTICALS CORPORATION (US) | 2009-07-16 | — | — | WO | disclosed |