Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759447 | 1.00 | POLB (0.55) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL5724602 | 0.87 | POLB (0.42) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL5415108 | 0.87 | POLB (0.42) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL5422425 | 0.87 | POLB (0.42) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL3079755 | 0.82 | POLB (0.57) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL21896031 | 0.82 | POLB (0.57) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL8742210 | 0.80 | POLB (0.55) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL8742209 | 0.80 | POLB (0.55) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL18629176 | 0.80 | POLB (0.55) | POLBL3MBTL1HSD11B1P2RX7HPGD | |
| SCHEMBL744692 | 0.80 | POLB (0.55) | POLBL3MBTL1HSD11B1P2RX7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876630-B | Preparation method and application of nano micelle based on bromo-monomer polymerization modification | 浙江理工大学 | 2022-07-12 | — | — | CN | claimed |
| CN-112876630-A | Preparation method and application of nano micelle based on brominated monomer polymerization modification | 浙江理工大学 | 2021-06-01 | — | — | CN | claimed |
| CN-105061697-A | Graphene oxide/polynorbornene composite material and preparation method thereof | UNIV JILIN | 2015-11-18 | — | — | CN | claimed |
| CN-104004162-A | Car roof composite electronic fabric, fullerene polymer and preparation method of fullerene polymer | NINGBO HIGH NEW DISTR YUANXIA SCIENCE & TECHNOLOGY CO LTD | 2014-08-27 | — | — | CN | claimed |
| US-20230096641-A1 | HPK1 ANTAGONISTS AND USES THEREOF | NIMBUS DISCOVERY, INC. | 2023-03-30 | — | — | US | disclosed |
| CN-112876630-B | Preparation method and application of nano micelle based on bromo-monomer polymerization modification | 浙江理工大学 | 2022-07-12 | — | — | CN | disclosed |
| CN-112876630-A | Preparation method and application of nano micelle based on brominated monomer polymerization modification | 浙江理工大学 | 2021-06-01 | — | — | CN | disclosed |
| WO-2019183793-A1 | N-HYDROXYPYRIDONE COMPOUND AND USE THEREOF | 华东理工大学 | 2019-10-03 | — | — | WO | disclosed |
| US-9862695-B2 | Monomer having N-acyl carbamoyl group and lactone skeleton, and polymeric compound | DAICEL CORPORATION (JP) | 2018-01-09 | — | — | US | disclosed |
| US-9725544-B2 | Preparation of conjugated aromatic/heteroaromatic oligomer-containing dielectric polymers and their applications | UNIVERSITY OF SOUTH CAROLINA (US) | 2017-08-08 | — | — | US | disclosed |
| US-9341947-B2 | Resist composition and method of forming resist pattern | TOKYO OHKA KOGYO CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| WO-2016037987-A1 | ORGANIC COMPOUNDS WITH A WOODY-PEPPERY ODOUR | GIVAUDAN SA (CH) | 2016-03-17 | — | — | WO | disclosed |
| US-4102994-A | Aliphatic amido-quaternary ammonium anti-microbial compounds | COLGATE-PALMOLIVE COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4091020-A | CONDENSATION, CATALYTIC DECARBOXYLATION | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4065497-A | MICROBIOCIDES, ALGICIDES | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4058625-A | Broad spectrum antimicrobial compositions containing tris-(hydroxymethyl)aminomethane and polyamines | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4046873-A | Alicyclic amido-quaternary ammonium anti-bacterial agents | COLGATE PALMOLIVE COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-4035174-A | MICROBIOCIDES | MERCK & CO., INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-4033748-A | MICROBIOCIDES | MERCK & CO., INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-4003934-A | ANTIMICROBIAL AGENTS, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230096641-A1 | HPK1 ANTAGONISTS AND USES THEREOF | PDXK, HIPK1, PCK1 | POLB 3344/4885L3MBTL1 1271/4885HSD11B1 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.