Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30779744 | 1.00 | GAA (0.69) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL22326350 | 0.87 | GAA (0.88) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL2566077 | 0.84 | GAA (0.69) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL2452322 | 0.84 | GAA (0.69) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL6570943 | 0.83 | GAA (0.74) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL7475276 | 0.83 | GAA (0.62) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL29556018 | 0.82 | GAA (0.67) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL5418885 | 0.82 | GAA (0.67) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL24507059 | 0.82 | GAA (0.71) | GAAALDH1A1CYP1A2RECQLKMT2A | |
| SCHEMBL12028883 | 0.82 | GAA (1.00) | GAAALDH1A1CYP1A2RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236945-A1 | PYRIDAZIN-3-CARBOXAMIDE COMPOUND AS TYK2 INHIBITOR | 广州费米子科技有限责任公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-117186074-A | Pyridazine-3-carboxamide compounds as TYK2 inhibitors | 广州费米子科技有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| US-8278425-B2 | N-substituted-aminomethylene bridged bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100249211-A1 | N-Substituted-Aminomethylene Bridged Bicyclic Nucleic Acid Analogs | IONIS PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
| EP-0818455-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-01-14 | — | — | EP | disclosed |
| WO-1997041128-A1 | 3-PYRAZOLIOMETHYLCEPHEM COMPOUNDS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249211-A1 | N-Substituted-Aminomethylene Bridged Bicyclic Nucleic Acid Analogs | NSUN2, RNMT, NSUN3 | GAA 2598/4885ALDH1A1 4378/4885CYP1A2 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.