Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | CASP1 | P29466 | 3/20 | 0.61 |
| ▸ | CASP7 | P55210 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550034 | 0.86 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8544863 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL8548676 | 0.81 | NPC1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL679245 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL7434126 | 0.80 | SLC22A12 (0.49) | SLC22A12KMT2AMAPTNPC1 | |
| SCHEMBL16540846 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL19767586 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL16540839 | 0.78 | PLK1 (0.52) | ALDH1A1KDM4EHPGDTSHRKMT2A | |
| SCHEMBL16540824 | 0.77 | MAPT (0.53) | ALDH1A1KDM4EHPGDCASP7GAA | |
| SCHEMBL12013388 | 0.76 | HTT (0.47) | ALDH1A1KDM4EHPGDHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |