Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.47 |
| ▸ | RARB | P10826 | 10/20 | 0.47 |
| ▸ | RARA | P10276 | 9/20 | 0.47 |
| ▸ | RARG | P13631 | 7/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 6/20 | 0.40 |
| ▸ | RXRG | P48443 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550221 | 1.00 | RXRA (0.47) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8544569 | 1.00 | RXRA (0.47) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8544567 | 1.00 | RXRA (0.47) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8550219 | 1.00 | RXRA (0.47) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8590653 | 0.88 | RXRA (0.42) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8590660 | 0.88 | RXRA (0.42) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8543983 | 0.88 | ALOX5 (0.41) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8590655 | 0.88 | RXRA (0.42) | RXRARARBRARARARGALOX5 | |
| SCHEMBL9156666 | 0.88 | RXRA (0.42) | RXRARARBRARARARGALOX5 | |
| SCHEMBL8590657 | 0.88 | RXRA (0.42) | RXRARARBRARARARGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591046-B1 | Chromene derivatives with a triene chain for use in the treatment of osteoporosis inflammatory diseases | ADIR (FR) | 1998-12-02 | — | — | EP | claimed |
| US-5391569-A | Treating osteoporosis, inflammatory disorders | ADIR ET COMPAGNIE (FR) | 1995-02-21 | — | — | US | claimed |
| EP-0591046-B1 | Chromene derivatives with a triene chain for use in the treatment of osteoporosis inflammatory diseases | ADIR (FR) | 1998-12-02 | — | — | EP | disclosed |
| US-5391569-A | Treating osteoporosis, inflammatory disorders | ADIR ET COMPAGNIE (FR) | 1995-02-21 | — | — | US | disclosed |
| EP-0591046-A1 | Chromene derivatives with a triene chain for use in the treatment of osteoporosis inflammatory diseases | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | disclosed |