SCHEMBL8544616

SCHEMBL8544616

CCOC(=O)NC1N=C(c2ccccn2)c2ccccc2N(CC(=O)C(C)(C)C)C1=O

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 3/20 0.67
CCKAR P32238 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7858054 0.84 CCKBR (0.67) CCKBRCCKAR
SCHEMBL4989782 0.84 CCKBR (0.67) CCKBRCCKAR
SCHEMBL4988847 0.83 CCKBR (0.61) CCKBRCCKAR
SCHEMBL1387612 0.82 CCKBR (0.78) CCKBRCCKAR
SCHEMBL1574452 0.82 CCKBR (0.85) CCKBRCCKAR
SCHEMBL8606948 0.82 SENP1 (0.57) CCKBRCCKAR
SCHEMBL8545459 0.82 SENP1 (0.57) CCKBRCCKAR
SCHEMBL1574231 0.82 CCKBR (0.85) CCKBRCCKAR
SCHEMBL4412665 0.81 CCKBR (0.61) CCKBRCCKAR
SCHEMBL8550608 0.81 SENP1 (0.58) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828765-B1 ETHYLENE-PENTENE-HEXENE COPOLYMER, PROCESS FOR ITS PREPARATION AND USE FOR THE PRODUCTION OF FILMS SASOL TECH PTY LTD (ZA) 1999-10-13 EP claimed
EP-0715624-B1 PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE YAMANOUCHI PHARMA CO LTD (JP) 1998-04-08 EP disclosed
US-5728829-A MULTISTAGE REACTION OF N-PROTECTED BENZOTRIAZOLYL GLYCINE DERIVATIVE WITH AMINOKETONE, THEN REACTION WITH AMMONIA AND ACID CATALYZED CYCLIZATION FERRING-RESEARCH LIMITED (GB) 1998-03-17 US disclosed
EP-0715624-A1 PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1996-06-12 EP disclosed
WO-1995006040-A1 BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-03-02 WO disclosed