Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | OGT | O15294 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545330 | 1.00 | GRIN2B (0.45) | GRIN2BMAOAMAOBOGTBCHE | |
| SCHEMBL8545326 | 1.00 | GRIN2B (0.45) | GRIN2BMAOAMAOBOGTBCHE | |
| SCHEMBL8547979 | 0.85 | GRIN2B (0.62) | GRIN2BMAOAMAOBOGTMEN1 | |
| SCHEMBL8541679 | 0.85 | GRIN2B (0.62) | GRIN2BMAOAMAOBOGTMEN1 | |
| SCHEMBL8540531 | 0.85 | GRIN2B (0.62) | GRIN2BMAOAMAOBOGTMEN1 | |
| SCHEMBL8547850 | 0.85 | GRIN2B (0.62) | GRIN2BMAOAMAOBOGTMEN1 | |
| SCHEMBL8547312 | 0.84 | MAOA (0.54) | GRIN2BMAOAMAOBOGTBCHE | |
| SCHEMBL8544591 | 0.84 | CARM1 (0.39) | GRIN2BBCHECARM1PRMT6MEN1 | |
| SCHEMBL8543293 | 0.84 | CARM1 (0.39) | GRIN2BBCHECARM1PRMT6MEN1 | |
| SCHEMBL8549242 | 0.84 | CARM1 (0.39) | GRIN2BBCHECARM1PRMT6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |