Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548180 | 0.92 | F10 (0.49) | PLAUF10PLGACACBF2 | |
| SCHEMBL6787163 | 0.81 | F10 (0.55) | PLAUF10PLGACACBF2 | |
| SCHEMBL8546892 | 0.80 | ACACB (0.55) | F10PLGACACBF2 | |
| SCHEMBL6792561 | 0.80 | ACACB (0.52) | PLAUF10PLGACACBF2 | |
| SCHEMBL7407648 | 0.76 | ACACB (0.49) | PLAUF10PLGACACBF2 | |
| SCHEMBL7304701 | 0.76 | F10 (0.56) | PLAUF10PLGF2 | |
| SCHEMBL6794066 | 0.74 | ACACB (0.54) | PLAUF10PLGACACBF2 | |
| SCHEMBL8549355 | 0.73 | F2 (0.52) | PLAUF10F2 | |
| SCHEMBL12125514 | 0.73 | PLG (0.56) | PLAUF10PLGF2 | |
| SCHEMBL27489065 | 0.71 | PLG (0.67) | PLAUF10PLGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783500-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |