Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.52 |
| ▸ | F10 | P00742 | 5/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 3/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546892 | 0.82 | ACACB (0.55) | F2F10 | |
| SCHEMBL6786293 | 0.81 | ACACB (0.53) | F2STS | |
| SCHEMBL12125514 | 0.78 | PLG (0.56) | F2F10PLAU | |
| SCHEMBL10194548 | 0.76 | SFRP1 (0.56) | STS | |
| SCHEMBL10194489 | 0.75 | ACACB (0.71) | — | |
| SCHEMBL7950245 | 0.75 | MMP13 (0.58) | — | |
| SCHEMBL1770698 | 0.75 | MMP13 (0.58) | — | |
| SCHEMBL7950060 | 0.74 | ITGB3 (0.51) | F2F10PLAU | |
| SCHEMBL10194537 | 0.74 | SFRP1 (0.53) | STS | |
| SCHEMBL7951841 | 0.73 | F10 (0.47) | F2F10PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783500-B1 | AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |