Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PTPRC | P08575 | 3/20 | 0.53 |
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343435 | 0.75 | TDP1 (1.00) | TDP1MAPTPTPRCS100A4L3MBTL1 | |
| Onychine SCHEMBL31040561 | 0.74 | ALDH1A1 (0.55) | TDP1PTPRCL3MBTL1MAPK1CES1 | |
| SCHEMBL27697020 | 0.74 | PTPRC (0.69) | TDP1MAPTPTPRCS100A4L3MBTL1 | |
| Onychine SCHEMBL8548579 | 0.74 | ALDH1A1 (0.55) | TDP1PTPRCL3MBTL1MAPK1CES1 | |
| SCHEMBL9055622 | 0.72 | TDP1 (0.78) | TDP1MAPTPTPRCS100A4L3MBTL1 | |
| SCHEMBL11245984 | 0.72 | PTPRC (0.67) | TDP1MAPTPTPRCS100A4BCHE | |
| SCHEMBL6415761 | 0.72 | SMN1; SMN2 (0.39) | TDP1MAPTPTPRCS100A4L3MBTL1 | |
| SCHEMBL2599382 | 0.71 | PTPRC (1.00) | TDP1MAPTPTPRCS100A4BCHE | |
| SCHEMBL2772220 | 0.71 | PTPRC (0.83) | TDP1MAPTPTPRCS100A4MAPK1 | |
| SCHEMBL11207794 | 0.71 | PTPRC (0.83) | TDP1MAPTPTPRCS100A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680471-B1 | 5-SUBSTITUTED 4-METHYL-5H-INDENO 1,2-b]PYRIDINES, THEIR PREPARATION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BASF AG (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5637554-A | 5-substituted 4-methyl-5H-indeno[3,2-b]pyridines and 9-substituted 1-methyl-9H-indeno[2,3-c]pyridines, their preparation and use as herbicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |
| EP-0680471-A1 | 5-SUBSTITUTED 4-METHYL-5H-INDENO 1,2-b]PYRIDINES, THEIR PREPARATION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017044-A1 | 5-SUBSTITUTED 4-METHYL-5H-INDENO[1,2-b]PYRIDINES AND 9-SUBSTITUTED 1-METHYL-IH-INDENO[2,1-c]PYRIDINES, THEIR PREPARATION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-04 | — | — | WO | disclosed |