Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Onychine SCHEMBL31040561 | 1.00 | ALDH1A1 (0.55) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| Cleistopholine SCHEMBL6358965 | 0.93 | ALDH1A1 (0.55) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL23235907 | 0.85 | ALDH1A1 (0.55) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL6408518 | 0.82 | TDP2 (0.55) | PTPRCCTSLCTSSPTPN13KMT2A | |
| SCHEMBL6597622 | 0.80 | NOS2 (0.43) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL7991158 | 0.80 | NOS2 (0.43) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL6407115 | 0.79 | TDP2 (0.55) | PTPRCCTSLCTSSPTPN13KMT2A | |
| SCHEMBL28588064 | 0.78 | ADORA2A (0.54) | ALDH1A1PTPRCMAOANPC1CYP3A4 | |
| SCHEMBL30886455 | 0.75 | ALDH1A1 (0.67) | ALDH1A1PTPRCMAOANPC1CYP3A4 | |
| SCHEMBL55743 | 0.75 | ALDH1A1 (0.67) | ALDH1A1PTPRCMAOANPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680471-B1 | 5-SUBSTITUTED 4-METHYL-5H-INDENO 1,2-b]PYRIDINES, THEIR PREPARATION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BASF AG (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5637554-A | 5-substituted 4-methyl-5H-indeno[3,2-b]pyridines and 9-substituted 1-methyl-9H-indeno[2,3-c]pyridines, their preparation and use as herbicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |
| EP-0680471-A1 | 5-SUBSTITUTED 4-METHYL-5H-INDENO 1,2-b]PYRIDINES, THEIR PREPARATION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | disclosed |
| EP-0662076-A1 | 2-AMINOALKYL-5-AMINOALKYLAMINO SUBSTITUTED ISOQUINOINDAZOLE-6-(2H)-ONES WITH ANTITUMOUR ACTIVITY | THE UNIVERSITY OF VERMONT (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994017044-A1 | 5-SUBSTITUTED 4-METHYL-5H-INDENO[1,2-b]PYRIDINES AND 9-SUBSTITUTED 1-METHYL-IH-INDENO[2,1-c]PYRIDINES, THEIR PREPARATION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-04 | — | — | WO | disclosed |
| US-4965272-A | EUPOLAURIDINE AND NONTOXIC CARRIER | UNIVERSITY OF MISSISSIPPI, THE | 1990-10-23 | — | — | US | disclosed |