Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544786 | 0.91 | GRIN2B (0.59) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8542863 | 0.90 | GRIN2B (0.47) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8549047 | 0.86 | GRIN1 (0.63) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8549343 | 0.85 | GRIN2B (0.59) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8547693 | 0.84 | GRIN2B (0.47) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8544371 | 0.84 | GRIN2B (0.47) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8548698 | 0.84 | GRIN2B (0.47) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8544337 | 0.84 | GRIN2B (0.57) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8546974 | 0.83 | GRIN2B (0.40) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8544989 | 0.81 | GRIN2B (0.59) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |